We have scheduled a restart of the repository server for this coming Monday, August 24, 2026, at 10:00 AM CEST. We kindly ask you to complete your work and save your progress beforehand. Please be aware that any unsaved changes to datasets may be lost during the restart.
If you don't see your institution, add your dataset to the main dataverse named "RepOD".
Select the dataverse to which you want to add the new dataset:
You need to Sign In/Sign Up to add a dataset.
Share this dataset on your favorite social media networks.
Sosiński, Oskar; Kołodziejski, Paweł; Leciejewska, Natalia; Pruszyńska, Ewa; Sassek, Maciej; Pawlak, Piotr, 2026, "LEAP2 regulates insulin secretion from INS-1E beta cells and rat pancreatic islets: An in vitro study", https://doi.org/10.18150/YQILMW, RepOD, V1
Learn about Data Citation Standards.
Description of the study’s context: The data was collected as part of a project „LEAP2 as a Modulator of Adipose Tissue and Pancreatic Metabolism in Type 2 Diabetes”, funded by the National Science Centre. The results relate to the impact of LEAP2 on insulin expression and secretion by INS-1E cells and rat pancreatic islets. The purpose of project is to expand knowledge about influence of novel hormone, LEAP2, on pancreatic islets, cell cultures representing pancreatic cells and later on obese, diabetic mouse. Research has in vitro character, data obtained through these experiments will be used for in vivo part of project. Data describes changes in expression of genes, proteins and insulin secretion under influence of various concentrations of LEAP2 hormone, when exposed to INS-1E cell line and pancreatic islets of rat. Data was measured with qPCR, western blot and ELISA techniques. Research was done in department of Animal Physiology and Biochemistry. This research was funded by the National Science Centre (Poland) (2021/41/B/NZ5/00446). More information available in the ReadMe file.
LEAP2, insulin, pancreas, in vitro, INS-1E, islet, rat
2029-08-17
This dataset is under embargo. Files in this dataset will be available from 2029-08-17.
Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.
According to the current settings, files in this dataset will be available from 2029-08-17.
Are you sure you want to lift the embargo?
Once you lift the embargo, you will not be able to set it again.
Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.
Use a Anonymized Private URL to allow those without Dataverse accounts to access your dataset. For more information about the Private URL feature, please refer to the User Guide.
Private URL has not been created.
"WARNING. This dataset has at least one published version. Those who have access to the Anonymized Private URL for this dataset may be able to use its accessible metadata to look up the full, not anonymized version of this dataset.
Are you sure you want to disable the Private URL? If you have shared the Private URL with others they will no longer be able to use it to access your dataset.
Use a Private URL to allow those without Dataverse accounts to access your dataset. For more information about the Private URL feature, please refer to the User Guide.
You will not be able to make changes to this dataset while it is in review.
This dataset cannot be published until Biological Sciences is published. Would you like to publish both right now?
Once you publish this dataset it must remain published.
Are you sure you want to republish this dataset?
Select if this is a minor or major version update.
This dataset cannot be published until Biological Sciences is published by its administrator.
This dataset cannot be published until Biological Sciences and Poznań University of Life Sciences are published.
Are you sure you want to deaccession? The selected version(s) will no longer be viewable by the public.
Please fill this out to prove you are not a robot.
