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Divergent Impact of Endotoxin Priming and Endotoxin Tolerance on Macrophage Responses to Cancer Cells

Version 2.0

Roy, Konkonika; Wrotek, Sylwia; Maciejewski, Bartosz, 2025, "Divergent Impact of Endotoxin Priming and Endotoxin Tolerance on Macrophage Responses to Cancer Cells", https://doi.org/10.18150/TUGFBK, RepOD, V2

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Description

Title for the dataset: 


 Divergent Impact of Endotoxin Priming and Endotoxin Tolerance on Macrophage Responses to Cancer Cells


GENERAL INFORMATION


Language: English


Principal investigator:


Roy Konkonika

https://orcid.org/0000-0002-3742-5649


Associate or co-investigators:


Wrotek Sylwia

https://orcid.org/0000-0001-8744-7822


Maciejewski Bartosz

https://orcid.org/0000-0003-3496-8805



Contact person for questions:


Roy Konkonika konkonika.roy@doktorant.umk.pl


Maciejewski Bartosz bartosz.maciejewski@umk.pl


Date and place of data collection: 

2022-2025

Department of Immunology

Faculty of Biological and Veterinary Sciences

Nicolaus Copernicus University in Toruń

Lwowska 1, 87-100 Toruń, Poland 


Keywords: endotoxin tolerance, cancer, M1/M2 phenotype, immunosuppression, tumor microenvironment


Funding


NCN PRELUDIUM BIS 2 nr 2020/39/O/NZ5/00915



Licence: CC-BY 4.0



DATA DESCRIPTION


The dataset includes results from in vitro interactions between immune cells (RAW 264.7 macrophages) and the tumor microenvironment (4T1 cells) under endotoxin tolerance (ET) conditions.


It contains spreadsheets, pictures, PDF and FCS files. 

Details regarding materials and methods are described in the article: 

Roy K, Jędrzejewski T, Sobocińska J, Spisz P, Maciejewski B, Hövelmeyer N, Passeri B, Wrotek S. Divergent impact of endotoxin priming and endotoxin tolerance on macrophage responses to cancer cells. Cell Immunol. 2025 Mar 1;411-412:104934.

https://doi.org/10.1016/j.cellimm.2025.104934


(2025-02-24)
Subject
Medicine, Health and Life Sciences
Keyword

endotoxin tolerance, cancer, M1/M2 phenotype, immunosuppression, tumor microenvironment

Related Publication

Roy K, Jędrzejewski T, Sobocińska J, Spisz P, Maciejewski B, Hövelmeyer N, Passeri B, Wrotek S. Divergent impact of endotoxin priming and endotoxin tolerance on macrophage responses to cancer cells. Cell Immunol. 2025 Mar 1;411-412:104934. https://www.sciencedirect.com/science/article/pii/S000887492500019X?via%3Dihub doi: 10.1016/j.cellimm.2025.104934

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MD5: f458118b5e23ef9145441bff9527bbe4
License: CC BY - Creative Commons Attribution 4.0
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