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Świeca, Michał, 2026, "Lipoxygenase and xanthine oxidase inhibition and antioxidant potential of fractions obtained by multi-step extraction of Artist's bracket and Red-belted bracket", https://doi.org/10.18150/SYQWDX, RepOD, V1
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Oxidative stress and inflammation play key roles in the development of many diseases. This study evaluated the potential of bioactive compounds derived from Red-belted Bracket and Artist’s Bracket mushrooms to mitigate these processes. Specifically, the study aimed to assess the antioxidant properties of mushroom extracts obtained using a multi-step extraction method, as well as their effects on the activity of pro-inflammatory enzymes, lipoxygenase (LOX) and xanthine oxidase (XO). Particular emphasis was placed on elucidating the underlying mechanisms of action and the kinetics of enzyme inhibition.
Stres oksydacyjny i stan zapalny odgrywają kluczową rolę w rozwoju wielu chorób. Niniejsze badanie oceniało potencjał związków bioaktywnych pochodzących z hubiaka pospolitego (Red-belted Bracket) oraz lakownicy spłaszczonej (Artist’s Bracket) w łagodzeniu tych procesów. Celem pracy była ocena właściwości przeciwutleniających ekstraktów grzybowych otrzymanych metodą wieloetapowej ekstrakcji, a także ich wpływu na aktywność enzymów prozapalnych — lipooksygenazy (LOX) oraz oksydazy ksantynowej (XO). Szczególną uwagę poświęcono wyjaśnieniu mechanizmów działania oraz kinetyce procesu inhibicji enzymów.
medical mushrooms, terpenoids, antioxidant activity, anti-inflammatory activity, lipoxygenase, enzymes inhibition, xanthine oxidase, multi-step extraction, grzyby medyczne, terpenoidy, aktywność antyoksydacyjna, aktywność przeciwzapalna, lipooksygenaza, hamowanie enzymów, oksydaza ksantynowa, ekstrakcja wieloetapowa
2028-01-01
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