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Janowska, Justyna; Zajdel, Karolina, 2024, "Measurements of myelin g-ratio from transmission electron microscopy images of rat brain sections 9 weeks after neonatal hypoxia-ischemia", https://doi.org/10.18150/1JE8K7, RepOD, V1
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In the study we evaluated the myelination in brain slices of control animals and animals exposed to neonatal hypoxia ischemia with the use of transmission electron microscopy. Analyses were performed on samples collected 9 weeks after the injury. Evaluated structures included striatum and corpus callosum (CC). The g-ratio parameter was used to evaluate the thickness of myelin sheaths and it was calculated from the measurements of inner and outer myelin diameters obtained with MyelTracer software, according to the provided formula (Figure 5C in the linked paper [Janowska et al.; Brain Pathology; 2024]).
The file contains the raw data collected during axon and myelin measurements using MyelTracer software. "Number" refers to the single axon analyzed. In the example name CT1;1;2: CT1 refers to sample type (for example: CT1 - control animal 1; HI1 - hypoxic-ischemic animal 1); 1 refers to image number; 2 refers to axon number.
g-ratio, TEM, myelin, neonatal hypoxia-ischemia
Justyna Janowska, Justyna Gargas, Karolina Zajdel, Michal Wieteska, Kamil Lipinski, Malgorzata Ziemka-Nalecz, Malgorzata Frontczak-Baniewicz, Joanna Sypecka; Oligodendrocyte progenitor cells’ fate after neonatal asphyxia—Puzzling implications for the development of hypoxic–ischemic encephalopathy. Brain Pathology. 2024. e13255. https://onlinelibrary.wiley.com/doi/10.1111/bpa.13255 doi: 10.1111/bpa.13255
CC BY - Creative Commons Attribution 4.0
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