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Witkowska Piłaszewicz, Olga, 2023, "Raw data to article: Are proteins such as MMP2, IGF1, IL-13, and IL-1ra valuable as fitness markers in racehorses during exercise?", https://doi.org/10.18150/HZFODF, RepOD, V3
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Raw data connected with article entitled "Are proteins such as MMP2, IGF1, IL-13, and IL-1ra valuable as fitness markers in racehorses during exercise?".
Files in this dataset there are 2 files with raw data (.tab) and 2 files (.txt) with descriptions of data, named accordingly. In a recent study, in which more than a thousand racehorses have been evaluated, three potential blood markers have been selected, which may enable early detection of horses at risk of injuries such as insulin-like growth factor 1 (IGF1), interleukin-1 receptor antagonist (IL-1ra) and matrix metalloproteinase 2 (MMP2). However, it was suggested that the cytokine concentrations indicate the athlete's status better than mRNA expression in blood cells. Thus, the purpose of this study was to evaluate changes in IGF1, MMP-2, and novel markers as interleukin-13 (IL-13). ELISA tests were performed on thirty-one racehorses [n=31] which were divided into an inexperienced [beginner] group [n=20] and an experienced [advanced] group [n=6]. In addition, differences between race and training session were evaluated. Blood samples were taken before and after exercise. The basal IGF1 concentration was lower in an inexperienced group (p<0.01) as well as IL-13 (p<0.05) in comparison to the experienced group. There were no differences between pre- and post-exercise samples, changes in multiples or between training and racing exercises. In conclusions, basal values of some biomarkers may appear to be more beneficial in forecasting horse performance.
inflammatory response, myokines, exercise, injury, cytokines
CC BY - Creative Commons Attribution 4.0
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