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Electrospun nanofibers loaded with marigold extract based on PVP/HPβCD and PCL/PVP scaffolds for wound healing applications

Version 1.0

Paczkowska-Walendowska, Magdalena, 2025, "Electrospun nanofibers loaded with marigold extract based on PVP/HPβCD and PCL/PVP scaffolds for wound healing applications", https://doi.org/10.18150/ZSDLKG, RepOD, V1

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Description

Dissolution.xlsx - data represent the percentage of chlorogenic acid released. Columns indicate the systems tested, rows the corresponding time points. Data are presented as a percentage. Electrospun nanofibers were subjected to dissolve experiments using Agilent 708-DS dissolving equipment (Santa Clara, CA, USA). A typical basket method was used, with 50 rpm and stirring at 37 ± 0.5 °C. Nanofibers (mass N1- 207,2/205,2/206,2 mg, N2 - 168,7/187,2/178,2 mg, N3 - 107,6/120,3/110,2 mg, N4 - 169,0/170,2/162,8 mg) were added to 300 mL of phosphate buffer (pH 5.5), which mimics the pH of skin. At regular intervals, liquid samples were collected, and the same volume of temperature-stabilized medium was swapped out. A nylon membrane filter with a mesh size of 0.45 µm was used to filter the samples. The concentration of the substance was determined by the HPLC method (https://doi.org/10.3390/ma17081736) and converted, relative to the weight, into the percentage of the substance released during the experiment.

Chlorogenic acid content in nanofibers: N1 - 4,64 ug/1mg of nanofibers, N2 - 4,60 ug/1 mg of nanofibers, N3 - 8,60 ug/1 mg of nanofibers, N4 - 9,16 ug/1 mg of nanofibers

Subject
Medicine, Health and Life Sciences
Keyword

nanofibers

Related Publication

Paczkowska-Walendowska, M.; Rosiak, N.; Plech, T.; Karpiński, T.M.; Miklaszewski, A.; Witkowska, K.; Jaskólski, M.; Erdem, C.; Cielecka-Piontek, J. Electrospun Nanofibers Loaded with Marigold Extract Based on PVP/HPβCD and PCL/PVP Scaffolds for Wound Healing Applications. Materials 2024, 17, 1736. https://doi.org/10.3390/ma17081736 https://doi.org/10.3390/ma17081736 doi: 10.3390/ma17081736

CC BY - Creative Commons Attribution 4.0 CC BY - Creative Commons Attribution 4.0

1 File
Dissolution.tab
Tabular Data - Original format: MS Excel (XLSX) - 681 B - Oct 15, 2025 - 1 Download
License: CC BY - Creative Commons Attribution 4.0
5 Variables, 10 Observations - UNF:6:tkKSeVmYfVuR1ntuNvtIEQ==
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