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Determination of the effect of astaxanthin on the physicochemical, structural, pharmacokinetic, and antioxidant properties of the polysaccharide/gelatin carriers.

Version 1.0

Łupina, Katarzyna, 2023, "Determination of the effect of astaxanthin on the physicochemical, structural, pharmacokinetic, and antioxidant properties of the polysaccharide/gelatin carriers.", https://doi.org/10.18150/VZGLDN, RepOD, V1

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Description

The dataset contains the results of research on the properties of films (hydrogels) obtained from a mixture of polysaccharides with emulsion-stabilizing effects (carboxymethyl cellulose (CMC), gum Arabic (GAR), octenyl succinic anhydride (OSA) starch, and water-soluble soy polysaccharides (WSSP)) and gelatin (GEL) supplemented with increasing concentrations (0, 0.25, 0.5, and 1% w/w) of astaxanthin. 

The characteristics of the obtained films included the determination of physicochemical (water content, pH, solubility, determination of surface hydrophobicity, swelling), optical properties (color stability, light transmission, transparency), structural properties (microscopy, Fourier transform infrared spectroscopy), barrier properties (water vapor permeability ), mechanical (puncture resistance, tensile strength, elongation at break, elastic modulus), pharmacokinetic (modeling of release kinetics) and antioxidants properties.

The study aimed to assess the functional properties of edible films based on polysaccharides (CMC, GAR, OSA, WSSP) and GEL (75/25 ratio) incorporated with water-soluble AstaSana astaxanthin (AST) in the amount of 0.25; 0.5; 1%.

Subject
Medicine, Health and Life Sciences
Keyword

polysaccharides, gelatin, astaxanthin, edible films

Related Publication

Łupina, K., Kowalczyk, D., & Kazimierczak, W. (2021). Gum Arabic/gelatin and water-soluble soy polysaccharides/gelatin blend films as carriers of astaxanthin—a comparative study of the kinetics of release and antioxidant properties. Polymers, 13(7), 1062 https://www.mdpi.com/2073-4360/13/7/1062 doi: https://doi.org/10.3390/polym13071062

CC BY - Creative Commons Attribution 4.0 CC BY - Creative Commons Attribution 4.0

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Films surface analysis -SEM.zip
ZIP Archive - 18.9 MB - Mar 23, 2023 - 19 Downloads
MD5: fe40de709e9cd75f0b44081282c0c2c0
License: CC BY - Creative Commons Attribution 4.0
SEM images of the surfaces of the AST-free and 1% AST-supplemented 75/25 blend films based on polysaccharides (CMC, GAR, OSA, WSSP) and gelatin (GEL). Files in .zip format supported by publicly available programs used to compress files. SEM photos in .tif format opened with Windows Photo Viewer.
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Analysis of film-forming solutions - cryoSEM.zip
ZIP Archive - 9.9 MB - Mar 23, 2023 - 19 Downloads
MD5: 8a8f98432e277736e8673d0b8871bb77
License: CC BY - Creative Commons Attribution 4.0
Images of AST-free and 1%AST-supplemented film-forming solutions based on polysaccharides (CMC, GAR, OSA, WSSP) and gelatin (GEL), were examined using the cryo-SEM technique. Files in .zip format supported by publicly available programs used to compress files. Cryo-SEM photos in .tif format opened with Windows Photo Viewer.
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Microscopic analysis of the AST solution and powder.zip
ZIP Archive - 16.2 MB - Mar 23, 2023 - 18 Downloads
MD5: d9daa6829ba345cb691532a1b6cdad7d
License: CC BY - Creative Commons Attribution 4.0
SEM photos of a water-soluble synthetic astaxanthin powder formulation. Images of a 1% aqueous solution of AST made using the cryo-SEM technique, optical and polarizing microscope. Files in .zip format supported by publicly available programs used to compress files. Packed photos in .jpg, .bmp, and .tif format supported by Windows Photo Viewer.
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Analysis of film-forming solutions - optical microscope.zip
ZIP Archive - 76.4 MB - Mar 23, 2023 - 13 Downloads
MD5: 1ba0fddd6c26f6380277fd1b64ae3ac6
License: CC BY - Creative Commons Attribution 4.0
Images of film-forming solutions obtained from a mixture of polysaccharides (CMC, GAR, OSA, WSSP) and GEL, doped with 0 and 1% AST, examined using an optical microscope. The .zip format used is supported by publicly available programs used to compress files. Photos of film-forming solutions in .bmp format opened with Windows Photo Viewer.
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Analysis of film-forming solutions - polarization.zip
ZIP Archive - 2.8 MB - Mar 23, 2023 - 19 Downloads
MD5: f6cd445f4e6894514eac85ad92409a00
License: CC BY - Creative Commons Attribution 4.0
Images of film-forming solutions obtained from a mixture of polysaccharides (GAR, WSSP) and GEL, supplemented with 0.5% AST taken with the polarizing microscope. The .zip format used is supported by publicly available programs used to compress files. Images of film-forming solutions in .tif format opened with Windows Photo Viewer.
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Color stability.zip
ZIP Archive - 35.2 KB - Mar 23, 2023 - 14 Downloads
MD5: 0a184837da2ef90cfb3ca35da7d1e76c
License: CC BY - Creative Commons Attribution 4.0
Color stability (represented by L*a*b* values) of films obtained from a mixture of polysaccharides (CMC, GAR, OSA, WSSP) and GEL, doped with increasing concentrations of AT (0; 0.25; 0.5, 1%). Storage condition: 60 days at 25 °C and 30 days at 60 °C. Files in .zip format supported by publicly available programs used to compress files. L*a*b* values generated by CQC53 software and converted to .csv and .ods format, supported e.g. by Microsoft Office Excel.
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FTIR ASTA.zip
ZIP Archive - 2.2 MB - Mar 23, 2023 - 19 Downloads
MD5: 35212deff8ce1c9c05dc42b45246e334
License: CC BY - Creative Commons Attribution 4.0
FTIR spectra of films obtained from a mixture of polysaccharides (CMC, GAR, OSA, WSSP) and GEL, doped with 0 and 1% AST. The .zip format used is supported by publicly available programs used to compress files. FTIR spectra in .tif format supported by Windows Photo Viewer. Editable data in .csv and .ods formats opened with e.g. Microsoft Office Excel.
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Puncture strength ASTA.zip
ZIP Archive - 1.9 MB - Mar 23, 2023 - 19 Downloads
MD5: dc7428b94070ce9b9983215e55ff5263
License: CC BY - Creative Commons Attribution 4.0
Puncture strength of films obtained from a mixture of polysaccharides (CMC, GAR, OSA, WSSP) and GEL, doped with increasing concentrations of AST (0, 0.25, 0.5, and 1%). The .zip format used is supported by publicly available programs used to compress files. Data were generated and can be processed by specialized Exponent software.
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UV-VIS ASTA.zip
ZIP Archive - 612.3 KB - Mar 23, 2023 - 20 Downloads
MD5: 6b25d67713a59bb841223742ab1f48cb
License: CC BY - Creative Commons Attribution 4.0
Effect of the increasing concentration of AST on the light transmission of the films obtained from the 75/25 blends of polysaccharides (CMC, GAR, OSA, WSSP) and GEL. Files in .zip format supported by publicly available programs used to compress files. Data (absorbances) generated using UV WinLab software and converted to .sp and .rls format, handled by Notepad, a text editor included with Microsoft Windows.
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Release.zip
ZIP Archive - 6.9 MB - Mar 23, 2023 - 15 Downloads
MD5: a3003762d995cf419aa9e1c3bb67b6c7
License: CC BY - Creative Commons Attribution 4.0
Release of AST from films based on a mixture of polysaccharides (CMC, GAR, OSA, WSSP) and GEL. DDSolver, i.e., the add-in software for Microsoft Excel, was used for modeling the AST release kinetics. Ten Release was carried out at 25 °C and 30 °C. Files in .zip format supported by publicly available programs used to compress files. Data on AST release (absorbances generated by the Gen5 program) and modeling of AST release kinetics were provided in the form of a Microsoft Office Excel spreadsheet (.xlsx and .ods formats).
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