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Wojtyłko, Monika; Froelich, Anna; Jadach, Barbara; Budnik, Irena; Krysztofiak, Julia; Białek, Antoni; Budna-Tukan, Joanna; Mlynarczyk, Dariusz T.; Nowicka, Ariadna B.; Kuczko, Wiesław; Wichniarek, Radosław; Szybowicz, Mirosław; Michniak-Kohn, Bozena B.; Lamprou, Dimitrios A.; Andrzej, Miklaszewski, 2026, "Stability study data of 3D-printed microneedle systems containing agomelatine", https://doi.org/10.18150/M9DI1R, RepOD, V1
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This dataset contains data from the stability study of 3D-printed microneedle systems containing agomelatine. The dataset includes chromatographic peak areas and calculated agomelatine concentrations and amounts for samples analyzed at day zero, after 3 months, and after 6 months of storage.
The tested systems included microneedles fabricated using MSLA and PolyJet 3D-printing techniques. The systems differed in microneedle geometry and drug-loading strategy. Agomelatine was introduced either by coating the microneedles with ethanol-based or suspension hydrogel formulations or by direct incorporation into a photocurable resin.
The dataset includes raw chromatographic peak area values, calculated concentrations, calculated agomelatine amounts, mean values, standard deviations, information on dilution, and values below the limit of quantification.
For further information, please consult the README.txt file.
agomelatine, 3D printing, stability, microneedle systems, transdermal drug delivery, franz cells, HPLC
Wojtyłko M, Osmałek T, Kuczko W, Wichniarek R, Nowicka AB, Szybowicz M, Mlynarczyk DT, Froelich A, Jadach B, Kordyl O, Budnik I, Białek A, Krysztofiak J, Michniak-Kohn B, Budna-Tukan J, Miklaszewski A, Lamprou DA. Agomelatine 3D-printed microneedles as a potential drug delivery system for the treatment of depression. International Journal of Pharmaceutics. 2026;690:126572 https://doi.org/10.1016/j.ijpharm.2026.126572 doi: 10.1016/j.ijpharm.2026.126572
CC BY - Creative Commons Attribution 4.0
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