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Grzymajło, Krzysztof, 2024, "Hypoxia impact Salmonella adhesion via T1F regulation", https://doi.org/10.18150/GP9M9N, RepOD, V1
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In this study we investigate the first stages of Salmonella Typhimurium infection under hypoxia conditions We found that low oxygen levels significantly decrease the bacterium's adhesion level. However, a high-binding phenotype of type 1 fimbriae can compensate for this deficiency. The study also identified a cross-talk between T1F and flagella expression in low-oxygen conditions, suggesting that altered flagellin expression levels may affect the bacterium's motility.
There are tabel of differential gene expression of Salmonella Typhimurium WT and Salmonella Typhimurium fimh knock-out grown in hypoxia and normoxia conditions.
RAW sequencing files were deposited in SRA database under accesion number SRP428426;
Salmonella, RNASeq
Grzymajło, K., Dutkiewicz, A., Czajkowska, J. et al. Salmonella adhesion is decreased by hypoxia due to adhesion and motility structure crosstalk. Vet Res 54, 99 (2023). https://veterinaryresearch.biomedcentral.com/articles/10.1186/s13567-023-01233-2 doi: 10.1186/s13567-023-01233-2
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