Files include the data presented in the manuscript entitled "3D-printed polycaprolactone implants modified with bioglass and Zn-doped bioglass " by I.Rajzer et al. (Materials 2023, 16(3), 1061;
https://doi.org/10.3390/ma16031061).
In this work, composite filaments in the form of sticks and 3D-printed scaffolds were investigated as a future component of an osteochondral implant. The first part of the work focused on the development of a filament modified with bioglass (BG) and Zn-doped BG obtained by injection molding. The main outcome was the manufacture of bioactive, strong, and flexible filament sticks of the required length, diameter, and properties. Then, sticks were used for scaffold production. We investigated the effect of bioglass addition on the samples mechanical and biological properties. The samples were analyzed by scanning electron microscopy, optical microscopy, infrared spectroscopy, and microtomography. The effect of bioglass addition on changes in the SBF mineralization process and cell morphology was evaluated. The presence of a spatial microstructure within the scaffolds affects their mechanical properties by reducing them. The tensile strength of the scaffolds compared to filaments was lower by 58–61%. In vitro mineralization experiments showed that apatite formed on scaffolds modified with BG after 7 days of immersion in SBF. Scaffold with Zn-doped BG showed a retarded apatite formation. Innovative 3D-printing filaments containing bioglasses have been successfully applied to print bioactive scaffolds with the surface suitable for cell attachment and proliferation.
Data (.txt. and .xlsx) includes:
1) Parameters of the injection process of PCL, PCL_BG and PCL_BG_Zn blends (Table 1)
2) Printing process parameters for PCL, PCL_BG, and PCL_BG_Zn filaments (Table 2)
3) Mechanical properties of PCL stick filaments: PCL, PCL_BG, PCL_BG_Zn (Table 3)
4) Mechanical properties of scaffolds made of PCL stick filaments: PCL, PCL_BG, PCL_BG_Zn (Table 4)
5) Calculation results based on µCT images (Table 5)
6) EDX analysis of PCL_BG (Fig. 3e) and PCL_BG_Zn (Fig 3g) filaments
7) ATR_FTIR spectra of filaments and powders (Fig 4)
8) The topographical scaffolds properties (Fig 5b)
9) EDX analysis of the scaffolds after 7 days of incubation in SBF (Fig 6d, 6e, 6f)
10) Histogram of the distribution of PCL_BG particles before and after incubation in SBF (Fig 7e, 7f) (Structure thickness distribution)
11) Cell viability MTT test results (Fig 9)
(2024)
