The following research assessed the effect of sodium butyrate (SB) on the expression of genes related to innate immune response and small heat shock proteins in the brains of broiler chickens. For this purpose 1000 eggs were incubated and divided into 4 groups. Three were injected with either 0.1, 0.3, or 0.5% doses of SB and the last one only with saline. Samples were collected post-mortem on day 42 of rearing. RNA isolated from the brain was tested for gene expression using a panel of the following: HSPB1, HSPB5, HSPB8, HSPB9, HSP70, IL-1β, IL-2, IL-4, IL-6, IL-8, IFNγ, IFNβ, TLR4, GR, BDNF, GSK3β, NR2A, CRH, NF-κB p65.
The dataset presents raw data related to the publication: Bełdowska, A., & Dunisławska, A. (2024). Influence of sodium butyrate administered in ovo on gene expression in the brain of broiler chickens. Animal Science Papers & Reports, 42(4). https://doi.org/10.2478/aspr-2023-0048
The data was obtained as a part of a project entitled "ActEpi: Activation of the epigenetic mechanisms in poultry through a programming of the gut microbiota", No. UMO-2021/43/D/NZ9/01548, financed by the National Science Center
(2025-02-09)