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Wojtyłko Monika; Froelich, Anna; Osmałek, Tomasz; Jadach, Barbara; Kordyl, Oliwia; Budnik, Irena; Krysztofiak, Julia; Białek, Antoni; Budna-Tukan, Joanna; Mlynarczyk, Dariusz T.; Wichniarek, Radosław; Szybowicz, Mirosław; Michniak-Kohn, Bozena B.; Lamprou, Dimitrios A.; Nowicka, Ariadna B; Miklaszewski, Andrzej; Kuczko, Wiesław, 2026, "Photostability data of 3D-printed microneedle systems containing agomelatine", https://doi.org/10.18150/DUABNS, RepOD, V1
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This dataset contains data from the photostability study of 3D-printed microneedle systems containing agomelatine. The dataset includes the results of agomelatine content determination in control samples and in samples exposed to light. The aim of the study was to evaluate the effect of light exposure on the amount of agomelatine in different variants of microneedle systems.
The analyzed systems included microneedles fabricated using MSLA and PolyJet 3D-printing techniques, mainly with cone-shaped and pyramid-shaped geometries. Agomelatine was introduced into the systems either by coating the microneedles with hydrogel formulations containing the drug or by direct incorporation of agomelatine into the photocurable resin.
For further information, please consult the readme.txt file.
agomelatine, 3D printing, photostability, microneedle systems, transdermal drug delivery, franz cells, HPLC
Wojtyłko M, Osmałek T, Kuczko W, Wichniarek R, Nowicka AB, Szybowicz M, Mlynarczyk DT, Froelich A, Jadach B, Kordyl O, Budnik I, Białek A, Krysztofiak J, Michniak-Kohn B, Budna-Tukan J, Miklaszewski A, Lamprou DA. Agomelatine 3D-printed microneedles as a potential drug delivery system for the treatment of depression. International Journal of Pharmaceutics. 2026;690:126572. https:/10.1016/j.ijpharm.2026.126572 doi: 10.1016/j.ijpharm.2026.126572
CC BY - Creative Commons Attribution 4.0
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