Files include the data presented in the manuscript entitled "Characterization of Magnesium and Zinc Forms of Sodalite Coatings on Ti6Al4V ELI for Potential Application in the Release of Drugs for Osteoporosis" by M. Sandomierski et al. (https://doi.org/10.3390/ma16041710).
The results concern the production of new drug carriers for osteoporosis. Osteoporosis is the most common metabolic disease of the skeletal system and is characterized by impaired bone strength. This translates into an increased risk of low-energy fractures, which means fractures caused by disproportionate force. This disease is quite insidious, its presence is usually detected only at an advanced stage, where treatment with pharmaceuticals does not produce sufficient results. It is obligatory to replace the weakened bone with an implant. For this reason, it is necessary to look at the possibilities of surface modification used in tissue engineering, which, in combination with the drugs for osteoporosis, i.e., bisphosphonates, may constitute a new and effective method for preventing the deterioration of the osteoporotic state. To achieve this purpose, titanium implants coated with magnesium or zinc zeolite were prepared. Both the sorption and release profiles differed depending on the type of ion in the zeolite structure. The successful release of risedronate rom the materials at a low level was proven. It can be concluded that the proposed solution will allow the preparation of endoprostheses for patients with bone diseases such as osteoporosis.
Data (.txt) includes:
1) Table 1. The content of elements in materials after drug sorption (wt. %).
2) Table 2. Coatings thickness, surface topography parameters and estimated coatings strength for each type of layers.
3) Figure 4. FTIR spectra of magnesium zeolite layers before and after drug sorption.
4) Figure 5. FTIR spectra of zinc zeolite layers before and after drug sorption.
5) Figure 6. Amount of drug retained on prepared materials
6) Figure 7. The amount of the drug released from the prepared materials.
Data (.csv) includes:
1) Table 1. The content of elements in materials after drug sorption (CSV)
2) Table 2. Coatings thickness, surface topography parameters (CSV)
3) Figure 4. FTIR spectra of magnesium zeolite layers (CSV)
4) Figure 5. FTIR spectra of zinc zeolite layers (CSV)
5) Figure 6. Amount of drug retained on prepared materials (CSV)
6) Figure 7. The amount of the drug released from the prepared materials (CSV)
