Files include the experimental data on bioactive glass containing zinc ions and a drug.
Data (.csv) includes:
DLS.tab - (Measurements for Zn-MBGN and Zn-MBGN-6MP were performed using a Zetasizer Nano ZS analyzer (Malvern Instruments Ltd., UK) at pH 7.)
DRUG_RELEASE.tab - (Analysis was done using a UV-VIS spectrophotometer UV-2600 (Shimadzu, Japan). The range of 300-400 nm (λ max = 320 nm) was applied for the measurements for desorption studies.)
FTIR.tab - (FT-IR analysis was performed for Zn-MBGN and Zn-MBGN-6MP using a LUMOS II FT-IR microscope (Brüker, Germany). Zn-MBGN and Zn-MBGN-6MP were analyzed using a Diamond EX-Press attachment (S.T. Japan, Japan). The spectral range was 4000-800 cm-1 with a resolution of 4 cm-1 at 60 scans for signal accumulation.)
TG.tab - (Zn-MBGN and Zn-MBGN-6MP were characterized using thermogravimetry. For this analysis, a STA 2500 Regulus analyzer (Netzsch) was employed. The temperature range was 25-850°C, with a nitrogen flow rate of 40 mL·min-1 and a heating rate of 10°C·min-1.)
Data (.tif) includes:
SEM_Zn-MBGN_10kx.tif - (Scanning Electron Microscopy measurements were done using a Quanta FEG (FEI) equipped with an Octane SDD EDS detector (EDAX). Analyses for Zn-MBGN were done under high vacuum mode, with an accelerating voltage of 10 kV and and magnification 10kx.)
SEM_Zn-MBGN_30kx.tif - (Scanning Electron Microscopy measurements were done using a Quanta FEG (FEI) equipped with an Octane SDD EDS detector (EDAX). Analyses for Zn-MBGN were done under high vacuum mode, with an accelerating voltage of 10 kV and and magnification 30kx.)
SEM_Zn-MBGN-6MP_10kx.tif - (Scanning Electron Microscopy measurements were done using a Quanta FEG (FEI) equipped with an Octane SDD EDS detector (EDAX). Analyses for Zn-MBGN-6MP were done under high vacuum mode, with an accelerating voltage of 10 kV and and magnification 10kx.)
SEM_Zn-MBGN-6MP_30kx.tif - (Scanning Electron Microscopy measurements were done using a Quanta FEG (FEI) equipped with an Octane SDD EDS detector (EDAX). Analyses for Zn-MBGN-6MP were done under high vacuum mode, with an accelerating voltage of 10 kV and and magnification 30kx.)
List of abbreviations:
SEM – scanning electron microscopy;
FTIR – Fourier-transform infrared spectroscopy;
DLS - Dynamic Light Scattering;
TG - Thermogravimetric Analysis;
Zn-MBGN - nanoparticles doped with zinc ions;
Zn-MBGN-6MP - nanoparticles doped with zinc ions and mercaptopurine.
Data refer to publication titled "Bioactive glass doped with zinc ions as a carrier for 6-mercaptopurine" prepared by Pyra et al.