Files include the data presented in the manuscript entitled " The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone " by Maciej B Hajduga et al. (Int J Mol Sci 2022 Sep 17;23(18):10899. doi: 10.3390/ijms231810899).
This work contains an analysis of the impact of modifying a bioresorbable polymer-polycaprolactone (PCL)-with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: Staphylococcus aureus ATCC 25293, Escherichia coli ATCC 25922, Candida albicans ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against C. albicans and S. aureus was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples.
Data (.xlsx) includes:
1) Overview of the number of microorganisms in individual preparations [CFU] and antibacterial efficacy [ABE] for PCL, PCL/GNP_0.5, , PCL/GNP_5, , PCL/GNP_10 samples (Table 1):
a) Table 1A. Staphylococcus aureus ATTC 25923 – initial density 1.5 x 10^5 CFU/ml
b) Table 1B. Escherichia coli ATTC 25922—Initial Density 1.5 × 10^5 CFU/mL
c) Table 1C. Candida albicans ATTC 10231—Initial Density 1.5 × 10^5 CFU/mL
2) Average antybacterial efficacy (ABE) values for S. aureus (Fig 6)
3) Average antybacterial efficacy (ABE) values for C. albicans (Fig 7)
(2024)
